Case study: Survival Analysis with a gene signature in cancer
Case study: Survival Analysis with a gene signature in cancer UGenome has the expertise to leverage publicly available data sets and perform survival analysis using a gene signature of interest. Challenges Cancer research involves the use of loss- and gain-of-function mouse models to test hypotheses. A major goal is to correlate those findings to humans. […]
Case study: Treatment Response prediction
UGenome leverages a multicohort analysis framework to discover biomarkers that predict treatment response. Selecting the right treatments for the right patients at the right time. Overall improved therapeutic outcomes for patients diagnosed with autoimmune disease.Challenges Immunomodulator therapies are ineffective in roughly half of patients diagnosed with autoimmune disease. Choosing the right treatment oftentimes involves a […]
MECO & UGEnome Case study | bone metastasis risk in breast cancer treatment
UGenome provides bioinformatics services in medical assessment for breast cancer treatment Background Fibrotic-like matrix stiffness pro- motes distinct metastatic phenotypes in cancer cells, which are preserved after transition to softer microen- vironments, such as bone marrow. Using differential gene expression analysis a score of mechanical conditioning (MeCo) associated with bone metastasis in patients with breast […]
Case Study with Robust Diagnostics – Metabolite Identification & Profiling
UGenome provides bioinformatics services for metabolite identification and profiling BACKGROUND Metabolomics is a powerful, unguided approach using LC-MS/MS to identify changes in metabolism Tinked to genotype, phenotype, health status, or environmental exposure LC-MS/MS data sets are complex, but software tools enable identification of compounds detected in each sample Analysis and integration of compound results is […]
