Case study: Survival Analysis with a gene signature in cancer

UGenome Case Study Survival Analysis November 2023

Case study: Survival Analysis with a gene signature in cancer UGenome has the expertise to leverage publicly available data sets and perform survival analysis using a gene signature of interest. Challenges Cancer research involves the use of loss- and gain-of-function mouse models to test hypotheses. A major goal is to correlate those findings to humans. […]

Case study: Treatment Response prediction

UGenome Case Study Anti-TNFa for IBD

UGenome leverages a multicohort analysis framework to discover biomarkers that predict treatment response. Selecting the right treatments for the right patients at the right time. Overall improved therapeutic outcomes for patients diagnosed with autoimmune disease.Challenges Immunomodulator therapies are ineffective in roughly half of patients diagnosed with autoimmune disease. Choosing the right treatment oftentimes involves a […]

MECO & UGEnome Case study | bone metastasis risk in breast cancer treatment

UGenome Case Study MECO Breast Cancer (7)

UGenome provides bioinformatics services in medical assessment for breast cancer treatment Background Fibrotic-like matrix stiffness pro- motes distinct metastatic phenotypes in cancer cells, which are preserved after transition to softer microen- vironments, such as bone marrow. Using differential gene expression analysis a score of mechanical conditioning (MeCo) associated with bone metastasis in patients with breast […]

3 Emerging Trends | Personalized Medicine

UGenome - Emerging Trends - Personalized Medicine

Suraj Sakaram & Panashe Nyengera  Tailoring Healthcare to Your Genes Can medicine be tailored to fit each individual’s unique needs?  That’s the goal of personalized medicine which aims to correct the “one size fits all” approach to healthcare and medication delivery by using an individual’s unique genetic profile. The difference in our genomes result in […]

2 Emerging Trends | Artificial Intelligence

UGenome - Emerging Trends - Artificial Intelligence

Suraj Sakaram & Panashe Nyengera  What breakthroughs can artificial intelligence help computational biologists make to help make personalized medicine personal? Artificial Intelligence, particularly machine learning, has made many breakthroughs in bioinformatics, aiding in the analysis and interpretation of large biological datasets. Machine learning algorithms, including neural networks and decision trees, are being adapted more efficiently […]

1 Emerging Trends | Bioinformatics

UGenome - Emerging Trends - Bioinformatics

Suraj Sakaram & Panashe Nyengera  What are the emerging trends and innovations in bioinformatics? In today’s world of ever-accelerating technological advancements, the fields of bioinformatics are no exception. As a fusion of biological research, computational science, and statistical methodologies, bioinformatics has become a cornerstone of modern biological research. Bioinformatics: Where Biology Meets Big Data The […]